Integrated exposure–response analysis of efficacy and safety of lurbinectedin to support the dose regimen in small-cell lung cancer

PURPOSE: These exposure–response (E–R) analyses integrated lurbinectedin effects on key efficacy and safety variables in relapsed SCLC to determine the adequacy of the dose regimen of 3.2 mg/m(2) 1-h intravenous infusion every 3 weeks (q3wk). METHODS: Logistic models and Cox regression analyses were...

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Detalles Bibliográficos
Autores principales: Fernández-Teruel, Carlos, Fudio, Salvador, Lubomirov, Rubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054899/
https://www.ncbi.nlm.nih.gov/pubmed/34739582
http://dx.doi.org/10.1007/s00280-021-04366-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054899/
https://www.ncbi.nlm.nih.gov/pubmed/34739582
http://dx.doi.org/10.1007/s00280-021-04366-3

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