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Integrated exposure–response analysis of efficacy and safety of lurbinectedin to support the dose regimen in small-cell lung cancer
PURPOSE: These exposure–response (E–R) analyses integrated lurbinectedin effects on key efficacy and safety variables in relapsed SCLC to determine the adequacy of the dose regimen of 3.2 mg/m(2) 1-h intravenous infusion every 3 weeks (q3wk). METHODS: Logistic models and Cox regression analyses were...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054899/ https://www.ncbi.nlm.nih.gov/pubmed/34739582 http://dx.doi.org/10.1007/s00280-021-04366-3 |