Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms

Cardiac action potential (AP) shape and propagation are regulated by several key dynamic factors such as ion channel recovery and intracellular Ca(2+) cycling. Experimental methods for manipulating AP electrical dynamics commonly use ion channel inhibitors that lack spatial and temporal specificity....

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Detalles Bibliográficos
Autores principales: Biasci, V., Santini, L., Marchal, G. A., Hussaini, S., Ferrantini, C., Coppini, R., Loew, L. M., Luther, S., Campione, M., Poggesi, C., Pavone, F. S., Cerbai, E., Bub, G., Sacconi, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054908/
https://www.ncbi.nlm.nih.gov/pubmed/35488105
http://dx.doi.org/10.1007/s00395-022-00933-8

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