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Automated glycan assembly of Streptococcus pneumoniae type 14 capsular polysaccharide fragments

S. pneumoniae is a major human pathogen with increasing antibiotic resistance. Pneumococcal vaccines consist of capsular polysaccharide (CPS) or their related fragments conjugated to a carrier protein. The repeating unit of S. pneumoniae type 14 CPS shares a core structure with the CPS of Group B St...

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Detalles Bibliográficos
Autores principales: Louçano, João, Both, Peter, Marchesi, Andrea, del Bino, Linda, Adamo, Roberto, Flitsch, Sabine, Salwiczek, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9054924/
https://www.ncbi.nlm.nih.gov/pubmed/35517348
http://dx.doi.org/10.1039/d0ra01803a