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Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer

The genetic basis of colorectal cancer (CRC) and its clinical associations remain poorly understood due to limited samples or targeted genes in current studies. Here, we perform ultradeep whole-exome sequencing on 1015 patients with CRC as part of the ChangKang Project. We identify 46 high-confident...

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Detalles Bibliográficos
Autores principales:	Zhao, Qi, Wang, Feng, Chen, Yan-Xing, Chen, Shifu, Yao, Yi-Chen, Zeng, Zhao-Lei, Jiang, Teng-Jia, Wang, Ying-Nan, Wu, Chen-Yi, Jing, Ying, Huang, You-Sheng, Zhang, Jing, Wang, Zi-Xian, He, Ming-Ming, Pu, Heng-Ying, Mai, Zong-Jiong, Wu, Qi-Nian, Long, Renwen, Zhang, Xiaoni, Huang, Tanxiao, Xu, Mingyan, Qiu, Miao-Zheng, Luo, Hui-Yan, Li, Yu-Hong, Zhang, Dong-Shen, Jia, Wei-Hua, Chen, Gong, Ding, Pei-Rong, Li, Li-Ren, Lu, Zheng-Hai, Pan, Zhi-Zhong, Xu, Rui-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055073/ https://www.ncbi.nlm.nih.gov/pubmed/35487942 http://dx.doi.org/10.1038/s41467-022-30062-8

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