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Solvent-induced selectivity of Williamson etherification in the pursuit of amides resistant against oxidative degradation
This article reports two discoveries. (1) 2-Methoxyethanol induces unprecedented selectivity for etherification of 5-hydroxy-2-nitrobenzic acids without forming undesired esters. (2) Such compounds are precursors for amides showing unusual robustness against oxidative degradation, essential for mole...
Autores principales: | Derr, James B., Clark, John A., Morales, Maryann, Espinoza, Eli M., Vadhin, Sandra, Vullev, Valentine I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055110/ https://www.ncbi.nlm.nih.gov/pubmed/35516219 http://dx.doi.org/10.1039/d0ra04465b |
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