Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes

An efficient synthesis of a variety of 2,5-diaryloxazole derivatives via a rhodium-catalyzed annulation of triazoles and aldehydes is achieved. Various oxazole derivatives could be obtained in good to excellent yields. A concise synthesis of antimycobaterial natural products balsoxin and texamine ha...

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Detalles Bibliográficos
Autores principales: Li, Jian, Zhu, Shang-Rong, Xu, Yue, Lu, Xue-Chen, Wang, Zheng-Bing, Liu, Li, Xu, De-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055139/
https://www.ncbi.nlm.nih.gov/pubmed/35517461
http://dx.doi.org/10.1039/d0ra03966g
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author Li, Jian
Zhu, Shang-Rong
Xu, Yue
Lu, Xue-Chen
Wang, Zheng-Bing
Liu, Li
Xu, De-feng
author_facet Li, Jian
Zhu, Shang-Rong
Xu, Yue
Lu, Xue-Chen
Wang, Zheng-Bing
Liu, Li
Xu, De-feng
author_sort Li, Jian
collection PubMed
description An efficient synthesis of a variety of 2,5-diaryloxazole derivatives via a rhodium-catalyzed annulation of triazoles and aldehydes is achieved. Various oxazole derivatives could be obtained in good to excellent yields. A concise synthesis of antimycobaterial natural products balsoxin and texamine has been achieved using this method.
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spelling pubmed-90551392022-05-04 Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes Li, Jian Zhu, Shang-Rong Xu, Yue Lu, Xue-Chen Wang, Zheng-Bing Liu, Li Xu, De-feng RSC Adv Chemistry An efficient synthesis of a variety of 2,5-diaryloxazole derivatives via a rhodium-catalyzed annulation of triazoles and aldehydes is achieved. Various oxazole derivatives could be obtained in good to excellent yields. A concise synthesis of antimycobaterial natural products balsoxin and texamine has been achieved using this method. The Royal Society of Chemistry 2020-06-30 /pmc/articles/PMC9055139/ /pubmed/35517461 http://dx.doi.org/10.1039/d0ra03966g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Jian
Zhu, Shang-Rong
Xu, Yue
Lu, Xue-Chen
Wang, Zheng-Bing
Liu, Li
Xu, De-feng
Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
title Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
title_full Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
title_fullStr Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
title_full_unstemmed Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
title_short Synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
title_sort synthesis of 2,5-diaryloxazoles through rhodium-catalyzed annulation of triazoles and aldehydes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055139/
https://www.ncbi.nlm.nih.gov/pubmed/35517461
http://dx.doi.org/10.1039/d0ra03966g
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