Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes

A simple silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes has been described. This strategy provides an efficient and practical avenue to access various deuterated electron-rich arenes, azaarenes and α-deuterated 2-alkyl azaarenes with good to exce...

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Detalles Bibliográficos
Autores principales: Dong, Baobiao, Cong, Xuefeng, Hao, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055237/
https://www.ncbi.nlm.nih.gov/pubmed/35518614
http://dx.doi.org/10.1039/d0ra02358b
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author Dong, Baobiao
Cong, Xuefeng
Hao, Na
author_facet Dong, Baobiao
Cong, Xuefeng
Hao, Na
author_sort Dong, Baobiao
collection PubMed
description A simple silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes has been described. This strategy provides an efficient and practical avenue to access various deuterated electron-rich arenes, azaarenes and α-deuterated 2-alkyl azaarenes with good to excellent deuterium incorporation utilizing D(2)O as the source of deuterium atoms.
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spelling pubmed-90552372022-05-04 Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes Dong, Baobiao Cong, Xuefeng Hao, Na RSC Adv Chemistry A simple silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes has been described. This strategy provides an efficient and practical avenue to access various deuterated electron-rich arenes, azaarenes and α-deuterated 2-alkyl azaarenes with good to excellent deuterium incorporation utilizing D(2)O as the source of deuterium atoms. The Royal Society of Chemistry 2020-07-06 /pmc/articles/PMC9055237/ /pubmed/35518614 http://dx.doi.org/10.1039/d0ra02358b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Dong, Baobiao
Cong, Xuefeng
Hao, Na
Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
title Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
title_full Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
title_fullStr Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
title_full_unstemmed Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
title_short Silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
title_sort silver-catalyzed regioselective deuteration of (hetero)arenes and α-deuteration of 2-alkyl azaarenes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055237/
https://www.ncbi.nlm.nih.gov/pubmed/35518614
http://dx.doi.org/10.1039/d0ra02358b
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AT congxuefeng silvercatalyzedregioselectivedeuterationofheteroarenesandadeuterationof2alkylazaarenes
AT haona silvercatalyzedregioselectivedeuterationofheteroarenesandadeuterationof2alkylazaarenes

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