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Longitudinal PET studies of mGluR5 in FXS using an FMR1 knockout mouse model

Fragile X syndrome (FXS) is a monogenic disorder characterized by intellectual disability and behavioral challenges. It is caused by aberrant methylation of the fragile X mental retardation 1 (FMR1) gene. Given the failure of clinical trials in FXS and growing evidence of a role of metabotropic glut...

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Detalles Bibliográficos
Autores principales:	Afshar, Sepideh, Lule, Sevda, Yuan, Gengyang, Qu, Xiying, Pan, Chuzhi, Whalen, Michael, Brownell, Anna-Liisa, Mody, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055256/ https://www.ncbi.nlm.nih.gov/pubmed/35582646 http://dx.doi.org/10.1515/tnsci-2022-0217

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