Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine

An effective synthetic method to achieve difluoromethylated oxazolidin-2-imine has been developed via visible-light promoted three-component tandem reaction of aryl allylamines, 2-BTSO2CF2H (BT = Benzothiazole) and isocyanates. This method features mild reaction conditions and good functional group...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Kun, Wei, Jun, Yan, Huihui, Sheng, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055360/
https://www.ncbi.nlm.nih.gov/pubmed/35518621
http://dx.doi.org/10.1039/d0ra04729e
_version_ 1784697392432414720
author Bao, Kun
Wei, Jun
Yan, Huihui
Sheng, Rong
author_facet Bao, Kun
Wei, Jun
Yan, Huihui
Sheng, Rong
author_sort Bao, Kun
collection PubMed
description An effective synthetic method to achieve difluoromethylated oxazolidin-2-imine has been developed via visible-light promoted three-component tandem reaction of aryl allylamines, 2-BTSO2CF2H (BT = Benzothiazole) and isocyanates. This method features mild reaction conditions and good functional group tolerance, and the reaction mechanism was confirmed by experiments and interpreted by quantum chemical calculations.
format Online
Article
Text
id pubmed-9055360
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90553602022-05-04 Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine Bao, Kun Wei, Jun Yan, Huihui Sheng, Rong RSC Adv Chemistry An effective synthetic method to achieve difluoromethylated oxazolidin-2-imine has been developed via visible-light promoted three-component tandem reaction of aryl allylamines, 2-BTSO2CF2H (BT = Benzothiazole) and isocyanates. This method features mild reaction conditions and good functional group tolerance, and the reaction mechanism was confirmed by experiments and interpreted by quantum chemical calculations. The Royal Society of Chemistry 2020-07-09 /pmc/articles/PMC9055360/ /pubmed/35518621 http://dx.doi.org/10.1039/d0ra04729e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Bao, Kun
Wei, Jun
Yan, Huihui
Sheng, Rong
Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
title Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
title_full Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
title_fullStr Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
title_full_unstemmed Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
title_short Visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
title_sort visible-light promoted three-component tandem reaction to synthesize difluoromethylated oxazolidin-2-imine
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055360/
https://www.ncbi.nlm.nih.gov/pubmed/35518621
http://dx.doi.org/10.1039/d0ra04729e
work_keys_str_mv AT baokun visiblelightpromotedthreecomponenttandemreactiontosynthesizedifluoromethylatedoxazolidin2imine
AT weijun visiblelightpromotedthreecomponenttandemreactiontosynthesizedifluoromethylatedoxazolidin2imine
AT yanhuihui visiblelightpromotedthreecomponenttandemreactiontosynthesizedifluoromethylatedoxazolidin2imine
AT shengrong visiblelightpromotedthreecomponenttandemreactiontosynthesizedifluoromethylatedoxazolidin2imine

Ejemplares similares