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Formation and characterization of crosslinks, including Tyr–Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

Dityrosine and ditryptophan bonds have been implied in protein crosslinking. This is associated with oxidative stress conditions including those involved in neurodegenerative pathologies and age-related processes. Formation of dityrosine and ditryptophan derives from radical–radical reactions involv...

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Detalles Bibliográficos
Autores principales: Figueroa, Juan David, Zárate, Ana María, Fuentes-Lemus, Eduardo, Davies, Michael J., López-Alarcón, Camilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055361/
https://www.ncbi.nlm.nih.gov/pubmed/35518626
http://dx.doi.org/10.1039/d0ra04051g