Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines

In this report, a green synthesis of N-sulfonyl amidines via the direct reaction of tertiary or secondary amines with sulfonyl azides is described. Transition metal- and catalyst-free conditions were used for the synthesis of biologically important N-sulfonyl amidines. Further studies showed that th...

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Detalles Bibliográficos
Autores principales: Kaboudin, Babak, Torabi, Saeed, Kazemi, Foad, Aoyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055405/
https://www.ncbi.nlm.nih.gov/pubmed/35515794
http://dx.doi.org/10.1039/d0ra04545d
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author Kaboudin, Babak
Torabi, Saeed
Kazemi, Foad
Aoyama, Hiroshi
author_facet Kaboudin, Babak
Torabi, Saeed
Kazemi, Foad
Aoyama, Hiroshi
author_sort Kaboudin, Babak
collection PubMed
description In this report, a green synthesis of N-sulfonyl amidines via the direct reaction of tertiary or secondary amines with sulfonyl azides is described. Transition metal- and catalyst-free conditions were used for the synthesis of biologically important N-sulfonyl amidines. Further studies showed that the reaction proceeded via in situ aerobic oxidation of amines under reflux conditions.
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spelling pubmed-90554052022-05-04 Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines Kaboudin, Babak Torabi, Saeed Kazemi, Foad Aoyama, Hiroshi RSC Adv Chemistry In this report, a green synthesis of N-sulfonyl amidines via the direct reaction of tertiary or secondary amines with sulfonyl azides is described. Transition metal- and catalyst-free conditions were used for the synthesis of biologically important N-sulfonyl amidines. Further studies showed that the reaction proceeded via in situ aerobic oxidation of amines under reflux conditions. The Royal Society of Chemistry 2020-07-17 /pmc/articles/PMC9055405/ /pubmed/35515794 http://dx.doi.org/10.1039/d0ra04545d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Kaboudin, Babak
Torabi, Saeed
Kazemi, Foad
Aoyama, Hiroshi
Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines
title Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines
title_full Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines
title_fullStr Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines
title_full_unstemmed Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines
title_short Transition metal- and catalyst-free one-pot green method for the synthesis of N-sulfonyl amidines via direct reaction of sulfonyl azides with amines
title_sort transition metal- and catalyst-free one-pot green method for the synthesis of n-sulfonyl amidines via direct reaction of sulfonyl azides with amines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055405/
https://www.ncbi.nlm.nih.gov/pubmed/35515794
http://dx.doi.org/10.1039/d0ra04545d
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AT kazemifoad transitionmetalandcatalystfreeonepotgreenmethodforthesynthesisofnsulfonylamidinesviadirectreactionofsulfonylazideswithamines
AT aoyamahiroshi transitionmetalandcatalystfreeonepotgreenmethodforthesynthesisofnsulfonylamidinesviadirectreactionofsulfonylazideswithamines

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