A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones

A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation has been developed. Starting from samples containing 3-(2-hydroxy-phenyl)-acrylic acids with 2-halide-benzenethiols, versatile biologically active 5-oxa-11-thia-benzofluoren-6-one compounds were efficiently synthes...

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Detalles Bibliográficos
Autores principales: Cai, Rongrong, Wei, Qicai, Xu, Runsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055437/
https://www.ncbi.nlm.nih.gov/pubmed/35519763
http://dx.doi.org/10.1039/d0ra04367b
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author Cai, Rongrong
Wei, Qicai
Xu, Runsheng
author_facet Cai, Rongrong
Wei, Qicai
Xu, Runsheng
author_sort Cai, Rongrong
collection PubMed
description A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation has been developed. Starting from samples containing 3-(2-hydroxy-phenyl)-acrylic acids with 2-halide-benzenethiols, versatile biologically active 5-oxa-11-thia-benzofluoren-6-one compounds were efficiently synthesized in good to high yields. This new methodology provides an economical approach toward C–S bond formation.
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spelling pubmed-90554372022-05-04 A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones Cai, Rongrong Wei, Qicai Xu, Runsheng RSC Adv Chemistry A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation has been developed. Starting from samples containing 3-(2-hydroxy-phenyl)-acrylic acids with 2-halide-benzenethiols, versatile biologically active 5-oxa-11-thia-benzofluoren-6-one compounds were efficiently synthesized in good to high yields. This new methodology provides an economical approach toward C–S bond formation. The Royal Society of Chemistry 2020-07-14 /pmc/articles/PMC9055437/ /pubmed/35519763 http://dx.doi.org/10.1039/d0ra04367b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Cai, Rongrong
Wei, Qicai
Xu, Runsheng
A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
title A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
title_full A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
title_fullStr A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
title_full_unstemmed A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
title_short A nickel-catalyzed tandem reaction involving cyclic esterification/C–S bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
title_sort nickel-catalyzed tandem reaction involving cyclic esterification/c–s bond formation for synthesizing 5-oxa-11-thia-benzofluoren-6-ones
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055437/
https://www.ncbi.nlm.nih.gov/pubmed/35519763
http://dx.doi.org/10.1039/d0ra04367b
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