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Label-free single-molecule identification of telomere G-quadruplexes with a solid-state nanopore sensor

Telomere sequences can spontaneously form G-quadruplexes (G4) in the presence of some cations. In view of their relevance to genetic processes and potential as therapeutic-targets, hitherto, a wealth of conventional techniques have been reported for interrogation of G4 conformation diversity and cor...

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Detalles Bibliográficos
Autores principales: Wang, Sen, Liang, Liyuan, Tang, Jing, Cai, Yao, Zhao, Chuanqi, Fang, Shaoxi, Wang, Huabin, Weng, Ting, Wang, Liang, Wang, Deqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055465/
https://www.ncbi.nlm.nih.gov/pubmed/35515777
http://dx.doi.org/10.1039/d0ra05083k