Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether

While iminium salts generated by the oxidation of amino ketene silyl acetals show intriguing reactivities to give useful γ-oxo-α-amino esters via reactions with silyl enol ethers in good yields, new iminium salts are also prepared by the oxidation of amino silyl enol ethers. They undergo facile addi...

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Autores principales: Shimizu, Makoto, Hata, Shingo, Kondo, Koichi, Murakami, Kazuhiro, Mizota, Isao, Zhu, Yusong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055599/
https://www.ncbi.nlm.nih.gov/pubmed/35516926
http://dx.doi.org/10.1039/d0ra05768a
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author Shimizu, Makoto
Hata, Shingo
Kondo, Koichi
Murakami, Kazuhiro
Mizota, Isao
Zhu, Yusong
author_facet Shimizu, Makoto
Hata, Shingo
Kondo, Koichi
Murakami, Kazuhiro
Mizota, Isao
Zhu, Yusong
author_sort Shimizu, Makoto
collection PubMed
description While iminium salts generated by the oxidation of amino ketene silyl acetals show intriguing reactivities to give useful γ-oxo-α-amino esters via reactions with silyl enol ethers in good yields, new iminium salts are also prepared by the oxidation of amino silyl enol ethers. They undergo facile addition reaction with various nucleophiles to give α-amino ketone derivatives in good yields.
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spelling pubmed-90555992022-05-04 Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether Shimizu, Makoto Hata, Shingo Kondo, Koichi Murakami, Kazuhiro Mizota, Isao Zhu, Yusong RSC Adv Chemistry While iminium salts generated by the oxidation of amino ketene silyl acetals show intriguing reactivities to give useful γ-oxo-α-amino esters via reactions with silyl enol ethers in good yields, new iminium salts are also prepared by the oxidation of amino silyl enol ethers. They undergo facile addition reaction with various nucleophiles to give α-amino ketone derivatives in good yields. The Royal Society of Chemistry 2020-07-24 /pmc/articles/PMC9055599/ /pubmed/35516926 http://dx.doi.org/10.1039/d0ra05768a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Shimizu, Makoto
Hata, Shingo
Kondo, Koichi
Murakami, Kazuhiro
Mizota, Isao
Zhu, Yusong
Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
title Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
title_full Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
title_fullStr Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
title_full_unstemmed Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
title_short Preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
title_sort preparation and facile addition reactions of iminium salts derived from amino ketene silyl acetal and amino silyl enol ether
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055599/
https://www.ncbi.nlm.nih.gov/pubmed/35516926
http://dx.doi.org/10.1039/d0ra05768a
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