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Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases

BACKGROUND: The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis. METHODS: This single-center study is a retrospective review of 17 patients with...

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Autores principales: Deventer, Niklas, Budny, Tymoteusz, Gosheger, Georg, de Vaal, Marieke, Burkhardt, Jana, Deventer, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055713/
https://www.ncbi.nlm.nih.gov/pubmed/35490224
http://dx.doi.org/10.1186/s12891-022-05362-1
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author Deventer, Niklas
Budny, Tymoteusz
Gosheger, Georg
de Vaal, Marieke
Burkhardt, Jana
Deventer, Nils
author_facet Deventer, Niklas
Budny, Tymoteusz
Gosheger, Georg
de Vaal, Marieke
Burkhardt, Jana
Deventer, Nils
author_sort Deventer, Niklas
collection PubMed
description BACKGROUND: The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis. METHODS: This single-center study is a retrospective review of 17 patients with primary ABCs of the pelvis. It examines the importance of polidocanol instillations as minimally invasive treatment option for ABCs of the pelvis compared to intralesional curettage or marginal resection. RESULTS: Seventeen patients with the diagnosis of a primary ABC of the pelvis were included in the study. Six patients were male (35%) and 11 patients female (65%); the mean age was 18 (9-49) years. The mean follow-up time was 50 months (12-136 months). The most common location of manifestation was the pubis (6; 35%), followed by the ilium (6; 35%), the sacrum (3; 18%) and the ischium (2; 12%). Eight patients were treated by intralesional curettage with the use of adjuvants, one patient by marginal resection, seven by sequential instillation of polidocanol and one patient by simple observation. Five patients received an additional transarterial embolization. After intralesional curettage local recurrence was detected in 4/8 cases (50%). After instillation therapy six patients (86%) had a stable disease without recurrence, only one patient (14%) had a persistent disease with need of additional treatment and was therefore converted to intralesional curettage without local recurrence in the follow-up. CONCLUSIONS: Sequential instillations of polidocanol are a promising, minimally invasive treatment method for ABCs of the pelvis and can be well combined with transarterial embolization.
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spelling pubmed-90557132022-05-01 Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases Deventer, Niklas Budny, Tymoteusz Gosheger, Georg de Vaal, Marieke Burkhardt, Jana Deventer, Nils BMC Musculoskelet Disord Research BACKGROUND: The aneurysmal bone cyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis. METHODS: This single-center study is a retrospective review of 17 patients with primary ABCs of the pelvis. It examines the importance of polidocanol instillations as minimally invasive treatment option for ABCs of the pelvis compared to intralesional curettage or marginal resection. RESULTS: Seventeen patients with the diagnosis of a primary ABC of the pelvis were included in the study. Six patients were male (35%) and 11 patients female (65%); the mean age was 18 (9-49) years. The mean follow-up time was 50 months (12-136 months). The most common location of manifestation was the pubis (6; 35%), followed by the ilium (6; 35%), the sacrum (3; 18%) and the ischium (2; 12%). Eight patients were treated by intralesional curettage with the use of adjuvants, one patient by marginal resection, seven by sequential instillation of polidocanol and one patient by simple observation. Five patients received an additional transarterial embolization. After intralesional curettage local recurrence was detected in 4/8 cases (50%). After instillation therapy six patients (86%) had a stable disease without recurrence, only one patient (14%) had a persistent disease with need of additional treatment and was therefore converted to intralesional curettage without local recurrence in the follow-up. CONCLUSIONS: Sequential instillations of polidocanol are a promising, minimally invasive treatment method for ABCs of the pelvis and can be well combined with transarterial embolization. BioMed Central 2022-04-30 /pmc/articles/PMC9055713/ /pubmed/35490224 http://dx.doi.org/10.1186/s12891-022-05362-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Deventer, Niklas
Budny, Tymoteusz
Gosheger, Georg
de Vaal, Marieke
Burkhardt, Jana
Deventer, Nils
Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
title Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
title_full Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
title_fullStr Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
title_full_unstemmed Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
title_short Aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
title_sort aneurysmal bone cyst of the pelvis and sacrum: a single-center study of 17 cases
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055713/
https://www.ncbi.nlm.nih.gov/pubmed/35490224
http://dx.doi.org/10.1186/s12891-022-05362-1
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