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Telomere shortening impairs alveolar regeneration
OBJECTIVES: Short telomeres in alveolar type 2 (AT2) cells have been associated with many lung diseases. The study aimed to investigate the regeneration capacity of AT2 cells with short telomeres by knocking out Tert in mice (G4 Tert ( −/− )) from the whole to the cellular level. MATERIALS AND METHO...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055893/ https://www.ncbi.nlm.nih.gov/pubmed/35274784 http://dx.doi.org/10.1111/cpr.13211 |