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Telomere shortening impairs alveolar regeneration

OBJECTIVES: Short telomeres in alveolar type 2 (AT2) cells have been associated with many lung diseases. The study aimed to investigate the regeneration capacity of AT2 cells with short telomeres by knocking out Tert in mice (G4 Tert ( −/− )) from the whole to the cellular level. MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales:	Zhang, Xin, Shi, Mengting, Zhao, Xi, Bin, Ennan, Hu, Yucheng, Tang, Nan, Dai, Huaping, Wang, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055893/ https://www.ncbi.nlm.nih.gov/pubmed/35274784 http://dx.doi.org/10.1111/cpr.13211

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