Insulin‐like growth factor 2 mRNA‐binding protein 2‐regulated alternative splicing of nuclear factor 1 C‐type causes excessive granulosa cell proliferation in polycystic ovary syndrome

OBJECTIVES: Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder. Insulin‐like growth factor 2 mRNA‐binding protein 2 (IGF2BP2) serves as an HMGA2 target gene to promote the proliferation of granulosa cells (GCs). However, it is still unclear whether IGF2BP2 participates in t...

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Detalles Bibliográficos
Autores principales: Zhao, Feiyan, Wu, Liang, Wang, Qin, Zhao, Xuehan, Chen, Tong, Yin, Chenghong, Yan, Long, Yang, Xiaokui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055906/
https://www.ncbi.nlm.nih.gov/pubmed/35293050
http://dx.doi.org/10.1111/cpr.13216

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