Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes

An efficient [4 + 2] benzannulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes was achieved under metal-free reaction conditions selectively delivering a wide range of polyfunctional benzenes in high yields respectively (up to 94% yield).

Detalles Bibliográficos
Autores principales: Jia, Qianfa, Lan, Yunfei, Ye, Xin, Lin, Yinhe, Ren, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055964/
https://www.ncbi.nlm.nih.gov/pubmed/35521133
http://dx.doi.org/10.1039/d0ra05251e
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author Jia, Qianfa
Lan, Yunfei
Ye, Xin
Lin, Yinhe
Ren, Qiao
author_facet Jia, Qianfa
Lan, Yunfei
Ye, Xin
Lin, Yinhe
Ren, Qiao
author_sort Jia, Qianfa
collection PubMed
description An efficient [4 + 2] benzannulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes was achieved under metal-free reaction conditions selectively delivering a wide range of polyfunctional benzenes in high yields respectively (up to 94% yield).
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spelling pubmed-90559642022-05-04 Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes Jia, Qianfa Lan, Yunfei Ye, Xin Lin, Yinhe Ren, Qiao RSC Adv Chemistry An efficient [4 + 2] benzannulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes was achieved under metal-free reaction conditions selectively delivering a wide range of polyfunctional benzenes in high yields respectively (up to 94% yield). The Royal Society of Chemistry 2020-08-06 /pmc/articles/PMC9055964/ /pubmed/35521133 http://dx.doi.org/10.1039/d0ra05251e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Jia, Qianfa
Lan, Yunfei
Ye, Xin
Lin, Yinhe
Ren, Qiao
Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
title Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
title_full Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
title_fullStr Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
title_full_unstemmed Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
title_short Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
title_sort direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055964/
https://www.ncbi.nlm.nih.gov/pubmed/35521133
http://dx.doi.org/10.1039/d0ra05251e
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