Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold

An unprecedented union of multi-component reactions to construct pyrazole- and pyranopyrazole-adorned 4H-chromene from simple reactants in water at ambient temperature is reported. This innovative tactic has integrated two distinct four-component reactions (4CRs) that occur transiently to form four...

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Autores principales: Kumaravel, Kandhasamy, Rajarathinam, Balakrishnan, Vasuki, Gnanasambandam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055991/
https://www.ncbi.nlm.nih.gov/pubmed/35521150
http://dx.doi.org/10.1039/d0ra05105e
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author Kumaravel, Kandhasamy
Rajarathinam, Balakrishnan
Vasuki, Gnanasambandam
author_facet Kumaravel, Kandhasamy
Rajarathinam, Balakrishnan
Vasuki, Gnanasambandam
author_sort Kumaravel, Kandhasamy
collection PubMed
description An unprecedented union of multi-component reactions to construct pyrazole- and pyranopyrazole-adorned 4H-chromene from simple reactants in water at ambient temperature is reported. This innovative tactic has integrated two distinct four-component reactions (4CRs) that occur transiently to form four new heterocycles via ten covalent bonds in a single step.
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spelling pubmed-90559912022-05-04 Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold Kumaravel, Kandhasamy Rajarathinam, Balakrishnan Vasuki, Gnanasambandam RSC Adv Chemistry An unprecedented union of multi-component reactions to construct pyrazole- and pyranopyrazole-adorned 4H-chromene from simple reactants in water at ambient temperature is reported. This innovative tactic has integrated two distinct four-component reactions (4CRs) that occur transiently to form four new heterocycles via ten covalent bonds in a single step. The Royal Society of Chemistry 2020-08-06 /pmc/articles/PMC9055991/ /pubmed/35521150 http://dx.doi.org/10.1039/d0ra05105e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Kumaravel, Kandhasamy
Rajarathinam, Balakrishnan
Vasuki, Gnanasambandam
Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold
title Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold
title_full Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold
title_fullStr Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold
title_full_unstemmed Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold
title_short Water-triggered union of multi-component reactions towards the synthesis of a 4H-chromene hybrid scaffold
title_sort water-triggered union of multi-component reactions towards the synthesis of a 4h-chromene hybrid scaffold
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055991/
https://www.ncbi.nlm.nih.gov/pubmed/35521150
http://dx.doi.org/10.1039/d0ra05105e
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AT vasukignanasambandam watertriggeredunionofmulticomponentreactionstowardsthesynthesisofa4hchromenehybridscaffold

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