Cargando…

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules

The T-cell immune response is a major determinant of effective SARS-CoV-2 clearance. Here, using the recently developed T-CoV bioinformatics pipeline (https://t-cov.hse.ru) we analyzed the peculiarities of the viral peptide presentation for the Omicron, Delta and Wuhan variants of SARS-CoV-2. First,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nersisyan, Stepan, Zhiyanov, Anton, Zakharova, Maria, Ishina, Irina, Kurbatskaia, Inna, Mamedov, Azad, Galatenko, Alexei, Shkurnikov, Maxim, Gabibov, Alexander, Tonevitsky, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055995/ https://www.ncbi.nlm.nih.gov/pubmed/35502206 http://dx.doi.org/10.7717/peerj.13354

Ejemplares similares

isomiRTar: a comprehensive portal of pan-cancer 5′-isomiR targeting
por: Nersisyan, Stepan, et al.
Publicado: (2022)

T-CoV: a comprehensive portal of HLA-peptide interactions affected by SARS-CoV-2 mutations
por: Nersisyan, Stepan, et al.
Publicado: (2021)

miRGTF-net: Integrative miRNA-gene-TF network analysis reveals key drivers of breast cancer recurrence
por: Nersisyan, Stepan, et al.
Publicado: (2021)

Association of HLA Class I Genotypes With Severity of Coronavirus Disease-19
por: Shkurnikov, Maxim, et al.
Publicado: (2021)

Differential co-expression network analysis with DCoNA reveals isomiR targeting aberrations in prostate cancer
por: Zhiyanov, Anton, et al.
Publicado: (2023)

MHC Class II Presentation in Autoimmunity
por: Ishina, Irina A., et al.
Publicado: (2023)

ExhauFS: exhaustive search-based feature selection for classification and survival regression
por: Nersisyan, Stepan, et al.
Publicado: (2022)

Differences in Presentation of SARS-CoV-2 Omicron Strain Variant BA.1–BA.5 Peptides by HLA Molecules
por: Nersisyan, S. A., et al.
Publicado: (2023)

Hypoxia-Induced miR-148a Downregulation Contributes to Poor Survival in Colorectal Cancer
por: Nersisyan, Stepan, et al.
Publicado: (2021)

Potential role of cellular miRNAs in coronavirus-host interplay
por: Nersisyan, Stepan, et al.
Publicado: (2020)

A novel approach for a joint analysis of isomiR and mRNA expression data reveals features of isomiR targeting in breast cancer
por: Nersisyan, Stepan, et al.
Publicado: (2022)

On the peptide binding affinity changes in population-specific HLA repertoires to the SARS-CoV-2 variants Delta and Omicron
por: Chen, Lu-Chun, et al.
Publicado: (2022)

Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2
por: Nersisyan, Stepan, et al.
Publicado: (2020)

HLA-A*01:01 allele diminishing in COVID-19 patients population associated with non-structural epitope abundance in CD8+ T-cell repertoire
por: Shkurnikov, Maxim, et al.
Publicado: (2023)

A Post-Processing Algorithm for miRNA Microarray Data
por: Nersisyan, Stepan, et al.
Publicado: (2020)

Development of a novel mathematical model that explains SARS-CoV-2 infection dynamics in Caco-2 cells
por: Staroverov, Vladimir, et al.
Publicado: (2023)

LAMA4-Regulating miR-4274 and Its Host Gene SORCS2 Play a Role in IGFBP6-Dependent Effects on Phenotype of Basal-Like Breast Cancer
por: Shkurnikov, Maxim, et al.
Publicado: (2019)

Comprehensive network of miRNA-induced intergenic interactions and a biological role of its core in cancer
por: Galatenko, Vladimir V., et al.
Publicado: (2018)

Endocytosis and Transcytosis of SARS-CoV-2 Across the Intestinal Epithelium and Other Tissue Barriers
por: Knyazev, Evgeny, et al.
Publicado: (2021)

Exhaustive Search of the Receptor Ligands by the CyCLOPS (Cytometry Cell-Labeling Operable Phage Screening) Technique
por: Ishina, Irina A., et al.
Publicado: (2020)

SARS-CoV-2 Mutations Lead to a Decrease in the Number of Tissue-Specific MicroRNA-Binding Regions in the Lung
por: Zhiyanov, A. P., et al.
Publicado: (2023)

Highly informative marker sets consisting of genes with low individual degree of differential expression
por: Galatenko, V. V., et al.
Publicado: (2015)

The Transcriptome of Type I Murine Astrocytes under Interferon-Gamma Exposure and Remyelination Stimulus
por: Kudriaeva, Anna, et al.
Publicado: (2017)

High-throughput identification of reference genes for research and clinical RT-qPCR analysis of breast cancer samples
por: Maltseva, Diana V, et al.
Publicado: (2013)

Dynamically regulated miRNA-mRNA networks revealed by exercise
por: Tonevitsky, Alexander G, et al.
Publicado: (2013)

ECM–Receptor Regulatory Network and Its Prognostic Role in Colorectal Cancer
por: Nersisyan, Stepan, et al.
Publicado: (2021)

Effect of the Expression of ELOVL5 and IGFBP6 Genes on the Metastatic Potential of Breast Cancer Cells
por: Nikulin, Sergey, et al.
Publicado: (2021)

HLA alleles measured from COVID-19 patient transcriptomes reveal associations with disease prognosis in a New York cohort
por: Warren, René L., et al.
Publicado: (2021)

Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides
por: Mamedov, Azad, et al.
Publicado: (2020)

Cumulative prognostic power of laminin genes in colorectal cancer
por: Galatenko, Vladimir V., et al.
Publicado: (2018)

Dynamics of the interaction between the receptor-binding domain of SARS-CoV-2 Omicron (B.1.1.529) variant and human angiotensin-converting enzyme 2
por: Antony, Priya, et al.
Publicado: (2022)

miRNome of inflammatory breast cancer
por: Maltseva, Diana V, et al.
Publicado: (2014)

Absence of enterotypes in the human gut microbiomes reanalyzed with non-linear dimensionality reduction methods
por: Bulygin, Ivan, et al.
Publicado: (2023)

Biologically-oriented mud volcano database: muddy_db
por: Remizovschi, Alexei, et al.
Publicado: (2021)

TransPrise: a novel machine learning approach for eukaryotic promoter prediction
por: Pachganov, Stepan, et al.
Publicado: (2019)

A guide for developing comprehensive systems biology maps of disease mechanisms: planning, construction and maintenance
por: Mazein, Alexander, et al.
Publicado: (2023)

Improving ancient DNA genome assembly
por: Seitz, Alexander, et al.
Publicado: (2017)

Homologous point transformer for multi-modality prostate image registration
por: Ruchti, Alexander, et al.
Publicado: (2022)

DACCOR–Detection, characterization, and reconstruction of repetitive regions in bacterial genomes
por: Seitz, Alexander, et al.
Publicado: (2018)

Excessive G–U transversions in novel allele variants in SARS-CoV-2 genomes
por: Panchin, Alexander Y., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j988vp0hkrnkf9tahcgpuurntv