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Two Cases Report of Intrathecal Tigecycline Therapy for Intracranial Infection with Acinetobacter baumannii and Review of Literatures

Objective: To explore the treatment scheme for intracranial infection with Acinetobacter baumannii. Methods: We retrospective analyzed two cases of patients of intracranial infection with Acinetobacter baumannii. Results: The intracranial infection was controlled effectively by the scheme to intrave...

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Detalles Bibliográficos
Autores principales: Huang, Guanlin, Lai, Wentao, Wu, Daxing, Huang, Qianliang, Zhong, Qi, Ye, Xinyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056109/
https://www.ncbi.nlm.nih.gov/pubmed/35502226
http://dx.doi.org/10.2147/IDR.S357087
Descripción
Sumario:Objective: To explore the treatment scheme for intracranial infection with Acinetobacter baumannii. Methods: We retrospective analyzed two cases of patients of intracranial infection with Acinetobacter baumannii. Results: The intracranial infection was controlled effectively by the scheme to intravenous“tigecycline + cefperazone-sulbactam”combined with intrathecal tigecycline injection, the two patients recover well with 21 months’ follow-up. Conclusions: Tigecycline-based drug scheme combined with intrathecal tigecycline injection can achieve the effect of controlling intracranial infection. Lumbar cisterna drainage tube plays a major role in controlling intracranial infection.