Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation

Pheochromocytoma is a rare catecholamine secreting neuroendocrine tumor arising from chromaffin cells of adrenal medulla with approximate prevalence of 0.1 to 0.6% in patients suffering from hypertension. Hypertensive control followed by surgical resection remains the primary treatment of choice. Al...

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Autores principales: Vankadari, Kousik, Boddula, Raman, Hegde, Aditya Gajanan, Chinte, Chimutai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056124/
https://www.ncbi.nlm.nih.gov/pubmed/35502282
http://dx.doi.org/10.1055/s-0042-1746177
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author Vankadari, Kousik
Boddula, Raman
Hegde, Aditya Gajanan
Chinte, Chimutai
author_facet Vankadari, Kousik
Boddula, Raman
Hegde, Aditya Gajanan
Chinte, Chimutai
author_sort Vankadari, Kousik
collection PubMed
description Pheochromocytoma is a rare catecholamine secreting neuroendocrine tumor arising from chromaffin cells of adrenal medulla with approximate prevalence of 0.1 to 0.6% in patients suffering from hypertension. Hypertensive control followed by surgical resection remains the primary treatment of choice. Although it is considered a slow growing benign tumor, it rarely leads to recurrence of tumor in the lymph nodes, liver, and lungs. Association of benign pheochromocytoma with familial or de novo Von Hippel-Lindau (VHL) mutations is well reported in literature. Here, we report a case of metastatic pheochromocytoma arising from commonly seen benign VHL mutation.
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spelling pubmed-90561242022-05-01 Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation Vankadari, Kousik Boddula, Raman Hegde, Aditya Gajanan Chinte, Chimutai World J Nucl Med Pheochromocytoma is a rare catecholamine secreting neuroendocrine tumor arising from chromaffin cells of adrenal medulla with approximate prevalence of 0.1 to 0.6% in patients suffering from hypertension. Hypertensive control followed by surgical resection remains the primary treatment of choice. Although it is considered a slow growing benign tumor, it rarely leads to recurrence of tumor in the lymph nodes, liver, and lungs. Association of benign pheochromocytoma with familial or de novo Von Hippel-Lindau (VHL) mutations is well reported in literature. Here, we report a case of metastatic pheochromocytoma arising from commonly seen benign VHL mutation. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-04-30 /pmc/articles/PMC9056124/ /pubmed/35502282 http://dx.doi.org/10.1055/s-0042-1746177 Text en World Association of Radiopharmaceutical and Molecular Therapy (WARMTH). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Vankadari, Kousik
Boddula, Raman
Hegde, Aditya Gajanan
Chinte, Chimutai
Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation
title Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation
title_full Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation
title_fullStr Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation
title_full_unstemmed Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation
title_short Metastatic Pheochromocytoma Diagnosed with (131) I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation
title_sort metastatic pheochromocytoma diagnosed with (131) i-mibg spect/ct imaging in a patient with pathogenic vhl mutation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056124/
https://www.ncbi.nlm.nih.gov/pubmed/35502282
http://dx.doi.org/10.1055/s-0042-1746177
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AT hegdeadityagajanan metastaticpheochromocytomadiagnosedwith131imibgspectctimaginginapatientwithpathogenicvhlmutation
AT chintechimutai metastaticpheochromocytomadiagnosedwith131imibgspectctimaginginapatientwithpathogenicvhlmutation

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