Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy

In the reported patient with advanced prostate cancer, a bone scan showed a false positive finding in thoracic vertebrae bone metastasis after external beam radiotherapy 2 months ago. An additional Tc-99m-prostate-specific membrane antigen scan showed a negative finding, although nonirradiated iliac...

Descripción completa

Detalles Bibliográficos
Autores principales: Liepe, Knut, Baehr, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056129/
https://www.ncbi.nlm.nih.gov/pubmed/35502276
http://dx.doi.org/10.1055/s-0042-1744200
_version_ 1784697565082550272
author Liepe, Knut
Baehr, Marcel
author_facet Liepe, Knut
Baehr, Marcel
author_sort Liepe, Knut
collection PubMed
description In the reported patient with advanced prostate cancer, a bone scan showed a false positive finding in thoracic vertebrae bone metastasis after external beam radiotherapy 2 months ago. An additional Tc-99m-prostate-specific membrane antigen scan showed a negative finding, although nonirradiated iliac bone metastasis was concordantly positive in both scans. The decrease in prostate-specific antigen-level from 156.6 ng/mL to 2.3 ng/mL indicates a strong effect of treatment, hence supporting false positivity in bone scan by flare phenomenon.
format Online
Article
Text
id pubmed-9056129
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format MEDLINE/PubMed
spelling pubmed-90561292022-05-01 Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy Liepe, Knut Baehr, Marcel World J Nucl Med In the reported patient with advanced prostate cancer, a bone scan showed a false positive finding in thoracic vertebrae bone metastasis after external beam radiotherapy 2 months ago. An additional Tc-99m-prostate-specific membrane antigen scan showed a negative finding, although nonirradiated iliac bone metastasis was concordantly positive in both scans. The decrease in prostate-specific antigen-level from 156.6 ng/mL to 2.3 ng/mL indicates a strong effect of treatment, hence supporting false positivity in bone scan by flare phenomenon. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-03-11 /pmc/articles/PMC9056129/ /pubmed/35502276 http://dx.doi.org/10.1055/s-0042-1744200 Text en World Association of Radiopharmaceutical and Molecular Therapy (WARMTH). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Liepe, Knut
Baehr, Marcel
Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
title Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
title_full Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
title_fullStr Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
title_full_unstemmed Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
title_short Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy
title_sort tc-99m-psma-spect/ct is superior to tc-99m-mdp-spect/ct in the staging of prostatic cancer with osseous metastases after external beam radiotherapy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056129/
https://www.ncbi.nlm.nih.gov/pubmed/35502276
http://dx.doi.org/10.1055/s-0042-1744200
work_keys_str_mv AT liepeknut tc99mpsmaspectctissuperiortotc99mmdpspectctinthestagingofprostaticcancerwithosseousmetastasesafterexternalbeamradiotherapy
AT baehrmarcel tc99mpsmaspectctissuperiortotc99mmdpspectctinthestagingofprostaticcancerwithosseousmetastasesafterexternalbeamradiotherapy

Ejemplares similares