Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid

An efficient and convenient iridium(iii) catalyzed ortho-C–H bond amidation of weakly coordinating benzamides treated with readily available sulfonyl azides as the amino source has been described. In this transformation, ionic liquids represents an ideal reaction medium, giving rise to a broad range...

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Autores principales: Jiao, Lin-Yu, Ning, Zi-Hui, Hong, Qian, Peng, Xin-Hua, Yin, Xiao-Mei, Liu, Shanshan, Chen, Huiyong, Li, Zhuo, Sun, Ming, Ma, Xiao-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056170/
https://www.ncbi.nlm.nih.gov/pubmed/35518216
http://dx.doi.org/10.1039/d0ra05527a
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author Jiao, Lin-Yu
Ning, Zi-Hui
Hong, Qian
Peng, Xin-Hua
Yin, Xiao-Mei
Liu, Shanshan
Chen, Huiyong
Li, Zhuo
Sun, Ming
Ma, Xiao-Xun
author_facet Jiao, Lin-Yu
Ning, Zi-Hui
Hong, Qian
Peng, Xin-Hua
Yin, Xiao-Mei
Liu, Shanshan
Chen, Huiyong
Li, Zhuo
Sun, Ming
Ma, Xiao-Xun
author_sort Jiao, Lin-Yu
collection PubMed
description An efficient and convenient iridium(iii) catalyzed ortho-C–H bond amidation of weakly coordinating benzamides treated with readily available sulfonyl azides as the amino source has been described. In this transformation, ionic liquids represents an ideal reaction medium, giving rise to a broad range of amidation products under mild conditions in the open air. This protocol offers moderate to excellent chemical yields, exclusive regioselectivities, and good functional group tolerance.
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spelling pubmed-90561702022-05-04 Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid Jiao, Lin-Yu Ning, Zi-Hui Hong, Qian Peng, Xin-Hua Yin, Xiao-Mei Liu, Shanshan Chen, Huiyong Li, Zhuo Sun, Ming Ma, Xiao-Xun RSC Adv Chemistry An efficient and convenient iridium(iii) catalyzed ortho-C–H bond amidation of weakly coordinating benzamides treated with readily available sulfonyl azides as the amino source has been described. In this transformation, ionic liquids represents an ideal reaction medium, giving rise to a broad range of amidation products under mild conditions in the open air. This protocol offers moderate to excellent chemical yields, exclusive regioselectivities, and good functional group tolerance. The Royal Society of Chemistry 2020-08-11 /pmc/articles/PMC9056170/ /pubmed/35518216 http://dx.doi.org/10.1039/d0ra05527a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Jiao, Lin-Yu
Ning, Zi-Hui
Hong, Qian
Peng, Xin-Hua
Yin, Xiao-Mei
Liu, Shanshan
Chen, Huiyong
Li, Zhuo
Sun, Ming
Ma, Xiao-Xun
Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
title Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
title_full Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
title_fullStr Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
title_full_unstemmed Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
title_short Iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
title_sort iridium-catalyzed ortho-selective carbon–hydrogen amidation of benzamides with sulfonyl azides in ionic liquid
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056170/
https://www.ncbi.nlm.nih.gov/pubmed/35518216
http://dx.doi.org/10.1039/d0ra05527a
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