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Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine
Protein is the material foundation of living things, and it directly takes part in and runs the process of living things itself. Predicting protein complexes helps us understand the structure and function of complexes, and it is an important foundation for studying how cells work. Genome-wide protei...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056223/ https://www.ncbi.nlm.nih.gov/pubmed/35502337 http://dx.doi.org/10.1155/2022/2273648 |
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author | Kaur, Arshpreet Chitre, Abhijit Wanjale, Kirti Kumar, Pankaj Miah, Shahajan Alguno, Arnold C. |
author_facet | Kaur, Arshpreet Chitre, Abhijit Wanjale, Kirti Kumar, Pankaj Miah, Shahajan Alguno, Arnold C. |
author_sort | Kaur, Arshpreet |
collection | PubMed |
description | Protein is the material foundation of living things, and it directly takes part in and runs the process of living things itself. Predicting protein complexes helps us understand the structure and function of complexes, and it is an important foundation for studying how cells work. Genome-wide protein interaction (PPI) data is growing as high-throughput experiments become more common. The aim of this research is that it provides a dual-tree complex wavelet transform which is used to find out about the structure of proteins. It also identifies the secondary structure of protein network. Many computer-based methods for predicting protein complexes have also been developed in the field. Identifying the secondary structure of a protein is very important when you are studying protein characteristics and properties. This is how the protein sequence is added to the distance matrix. The scope of this research is that it can confidently predict certain protein complexes rapidly, which compensates for shortcomings in biological research. The three-dimensional coordinates of C atom are used to do this. According to the texture information in the distance matrix, the matrix is broken down into four levels by the double-tree complex wavelet transform because it has four levels. The subband energy and standard deviation in different directions are taken, and then, the two-dimensional feature vector is used to show the secondary structure features of the protein in a way that is easy to understand. Then, the KNN and SVM classifiers are used to classify the features that were found. Experiments show that a new feature called a dual-tree complex wavelet can improve the texture granularity and directionality of the traditional feature extraction method, which is called secondary structure. |
format | Online Article Text |
id | pubmed-9056223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-90562232022-05-01 Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine Kaur, Arshpreet Chitre, Abhijit Wanjale, Kirti Kumar, Pankaj Miah, Shahajan Alguno, Arnold C. Biomed Res Int Research Article Protein is the material foundation of living things, and it directly takes part in and runs the process of living things itself. Predicting protein complexes helps us understand the structure and function of complexes, and it is an important foundation for studying how cells work. Genome-wide protein interaction (PPI) data is growing as high-throughput experiments become more common. The aim of this research is that it provides a dual-tree complex wavelet transform which is used to find out about the structure of proteins. It also identifies the secondary structure of protein network. Many computer-based methods for predicting protein complexes have also been developed in the field. Identifying the secondary structure of a protein is very important when you are studying protein characteristics and properties. This is how the protein sequence is added to the distance matrix. The scope of this research is that it can confidently predict certain protein complexes rapidly, which compensates for shortcomings in biological research. The three-dimensional coordinates of C atom are used to do this. According to the texture information in the distance matrix, the matrix is broken down into four levels by the double-tree complex wavelet transform because it has four levels. The subband energy and standard deviation in different directions are taken, and then, the two-dimensional feature vector is used to show the secondary structure features of the protein in a way that is easy to understand. Then, the KNN and SVM classifiers are used to classify the features that were found. Experiments show that a new feature called a dual-tree complex wavelet can improve the texture granularity and directionality of the traditional feature extraction method, which is called secondary structure. Hindawi 2022-04-23 /pmc/articles/PMC9056223/ /pubmed/35502337 http://dx.doi.org/10.1155/2022/2273648 Text en Copyright © 2022 Arshpreet Kaur et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Kaur, Arshpreet Chitre, Abhijit Wanjale, Kirti Kumar, Pankaj Miah, Shahajan Alguno, Arnold C. Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine |
title | Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine |
title_full | Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine |
title_fullStr | Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine |
title_full_unstemmed | Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine |
title_short | Recognition of Protein Network for Bioinformatics Knowledge Analysis Using Support Vector Machine |
title_sort | recognition of protein network for bioinformatics knowledge analysis using support vector machine |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056223/ https://www.ncbi.nlm.nih.gov/pubmed/35502337 http://dx.doi.org/10.1155/2022/2273648 |
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