Development of long-circulating lapachol nanoparticles: formation, characterization, pharmacokinetics, distribution and cytotoxicity

Lapachol is an active compound for the treatment of malignant brain glioma. However, its physicochemical properties limit its clinical application. The purpose of this study is to develop a nano-drug delivery system (LPC-LP) loaded with lapachol (LPC), which remarkably prolongs the half-life in the...

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Detalles Bibliográficos
Autores principales: Chen, Qunying, Bai, Lu, Zhou, Xuelin, Xu, Pingxiang, Li, Xiaorong, Xu, Huanli, Zheng, Yuanyuan, Zhao, Yuming, Lu, Shousi, Xue, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056296/
https://www.ncbi.nlm.nih.gov/pubmed/35518271
http://dx.doi.org/10.1039/d0ra05752e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056296/
https://www.ncbi.nlm.nih.gov/pubmed/35518271
http://dx.doi.org/10.1039/d0ra05752e

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