ortho-Naphthoquinone-catalyzed aerobic oxidation of amines to fused pyrimidin-4(3H)-ones: a convergent synthetic route to bouchardatine and sildenafil

A facile access to fused pyrimidin-4(3H)-one derivatives has been established by using the metal-free ortho-naphthoquinone-catalyzed aerobic cross-coupling reactions of amines. The utilization of two readily available amines allowed a direct coupling strategy to quinazolinone natural product, boucha...

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Detalles Bibliográficos
Autores principales: Kim, Kyeongha, Kim, Hun Young, Oh, Kyungsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056348/
https://www.ncbi.nlm.nih.gov/pubmed/35520643
http://dx.doi.org/10.1039/d0ra06820a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056348/
https://www.ncbi.nlm.nih.gov/pubmed/35520643
http://dx.doi.org/10.1039/d0ra06820a

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