Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties

Lawsone (2-hydroxynaphthalene-1,4-dione) is a natural product which shows significant biological activity. Aminomethylnaphthoquinone Mannich bases derived from lawsone constitute an interesting class of naphthoquinones and/or their metal complexes have demonstrated a series of important biological p...

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Autores principales: Olyaei, Abolfazl, Sadeghpour, Mahdieh, Khalaj, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056394/
https://www.ncbi.nlm.nih.gov/pubmed/35516010
http://dx.doi.org/10.1039/d0ra05717g
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author Olyaei, Abolfazl
Sadeghpour, Mahdieh
Khalaj, Mehdi
author_facet Olyaei, Abolfazl
Sadeghpour, Mahdieh
Khalaj, Mehdi
author_sort Olyaei, Abolfazl
collection PubMed
description Lawsone (2-hydroxynaphthalene-1,4-dione) is a natural product which shows significant biological activity. Aminomethylnaphthoquinone Mannich bases derived from lawsone constitute an interesting class of naphthoquinones and/or their metal complexes have demonstrated a series of important biological properties. So, this review aimed to document the publications concerning the synthesis of aminomethylnaphthoquinone Mannich bases from lowsone, aldehydes and amines and their metal complexes using different conditions, and investigation of their applications.
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spelling pubmed-90563942022-05-04 Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties Olyaei, Abolfazl Sadeghpour, Mahdieh Khalaj, Mehdi RSC Adv Chemistry Lawsone (2-hydroxynaphthalene-1,4-dione) is a natural product which shows significant biological activity. Aminomethylnaphthoquinone Mannich bases derived from lawsone constitute an interesting class of naphthoquinones and/or their metal complexes have demonstrated a series of important biological properties. So, this review aimed to document the publications concerning the synthesis of aminomethylnaphthoquinone Mannich bases from lowsone, aldehydes and amines and their metal complexes using different conditions, and investigation of their applications. The Royal Society of Chemistry 2020-08-17 /pmc/articles/PMC9056394/ /pubmed/35516010 http://dx.doi.org/10.1039/d0ra05717g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Olyaei, Abolfazl
Sadeghpour, Mahdieh
Khalaj, Mehdi
Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
title Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
title_full Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
title_fullStr Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
title_full_unstemmed Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
title_short Mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
title_sort mannich bases derived from lawsone and their metal complexes: synthetic strategies and biological properties
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056394/
https://www.ncbi.nlm.nih.gov/pubmed/35516010
http://dx.doi.org/10.1039/d0ra05717g
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AT khalajmehdi mannichbasesderivedfromlawsoneandtheirmetalcomplexessyntheticstrategiesandbiologicalproperties

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