Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems

Covalent attachment of human serum albumin protein to the surface of spherical lipoic acid capped silver nanoparticles results in the generation of stable nanoparticle–protein hybrids with well defined surface composition. Enhanced stability towards oxidation and in the presence of complex media wit...

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Detalles Bibliográficos
Autores principales: Guzmán-Soto, Irene, Omole, Mary, Alarcon, Emilio I., McTiernan, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056624/
https://www.ncbi.nlm.nih.gov/pubmed/35516471
http://dx.doi.org/10.1039/d0ra07080g
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author Guzmán-Soto, Irene
Omole, Mary
Alarcon, Emilio I.
McTiernan, Christopher D.
author_facet Guzmán-Soto, Irene
Omole, Mary
Alarcon, Emilio I.
McTiernan, Christopher D.
author_sort Guzmán-Soto, Irene
collection PubMed
description Covalent attachment of human serum albumin protein to the surface of spherical lipoic acid capped silver nanoparticles results in the generation of stable nanoparticle–protein hybrids with well defined surface composition. Enhanced stability towards oxidation and in the presence of complex media with high ionic strength, holds promise towards the use of these conjugates as therapeutics in biomedical applications and sensing.
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spelling pubmed-90566242022-05-04 Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems Guzmán-Soto, Irene Omole, Mary Alarcon, Emilio I. McTiernan, Christopher D. RSC Adv Chemistry Covalent attachment of human serum albumin protein to the surface of spherical lipoic acid capped silver nanoparticles results in the generation of stable nanoparticle–protein hybrids with well defined surface composition. Enhanced stability towards oxidation and in the presence of complex media with high ionic strength, holds promise towards the use of these conjugates as therapeutics in biomedical applications and sensing. The Royal Society of Chemistry 2020-09-04 /pmc/articles/PMC9056624/ /pubmed/35516471 http://dx.doi.org/10.1039/d0ra07080g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Guzmán-Soto, Irene
Omole, Mary
Alarcon, Emilio I.
McTiernan, Christopher D.
Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
title Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
title_full Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
title_fullStr Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
title_full_unstemmed Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
title_short Lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
title_sort lipoic acid capped silver nanoparticles: a facile route to covalent protein capping and oxidative stability within biological systems
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056624/
https://www.ncbi.nlm.nih.gov/pubmed/35516471
http://dx.doi.org/10.1039/d0ra07080g
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