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Molecular crowding induces primer extension by RNA polymerase through base stacking beyond Watson–Crick rules
The polymerisation of nucleic acids is essential for copying genetic information correctly to the next generations, whereas mispolymerisation could promote genetic diversity. It is possible that in the prebiotic era, polymerases might have used mispolymerisation to accelerate the diversification of...
Autores principales: | Takahashi, Shuntaro, Okura, Hiromichi, Chilka, Pallavi, Ghosh, Saptarshi, Sugimoto, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056655/ https://www.ncbi.nlm.nih.gov/pubmed/35515060 http://dx.doi.org/10.1039/d0ra06502a |
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