Cargando…

Molecular crowding induces primer extension by RNA polymerase through base stacking beyond Watson–Crick rules

The polymerisation of nucleic acids is essential for copying genetic information correctly to the next generations, whereas mispolymerisation could promote genetic diversity. It is possible that in the prebiotic era, polymerases might have used mispolymerisation to accelerate the diversification of...

Descripción completa

Detalles Bibliográficos
Autores principales: Takahashi, Shuntaro, Okura, Hiromichi, Chilka, Pallavi, Ghosh, Saptarshi, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056655/
https://www.ncbi.nlm.nih.gov/pubmed/35515060
http://dx.doi.org/10.1039/d0ra06502a

Ejemplares similares