Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities. Sponges which belong to the order Dictyoceratida are distinctly classified into 5 families: Dysideidae, Irciniidae, Spongiidae, Th...

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Autores principales: Abdelaleem, Enas Reda, Samy, Mamdouh Nabil, Desoukey, Samar Yehia, Liu, Miaomiao, Quinn, Ronald J., Abdelmohsen, Usama Ramadan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056847/
https://www.ncbi.nlm.nih.gov/pubmed/35514397
http://dx.doi.org/10.1039/d0ra04408c
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author Abdelaleem, Enas Reda
Samy, Mamdouh Nabil
Desoukey, Samar Yehia
Liu, Miaomiao
Quinn, Ronald J.
Abdelmohsen, Usama Ramadan
author_facet Abdelaleem, Enas Reda
Samy, Mamdouh Nabil
Desoukey, Samar Yehia
Liu, Miaomiao
Quinn, Ronald J.
Abdelmohsen, Usama Ramadan
author_sort Abdelaleem, Enas Reda
collection PubMed
description Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities. Sponges which belong to the order Dictyoceratida are distinctly classified into 5 families: Dysideidae, Irciniidae, Spongiidae, Thorectidae, and Verticilliitidae. In this review, compounds isolated from Dictyoceratida sponges were discussed with their biological potential within the period 2013 to December 2019. Moreover, analysis of the physicochemical properties of these marine natural products was investigated and the results showed that 78% of the compounds have oral bioavailability potential. This review highlights sponges of the order Dictyoceratida as exciting source for discovery of new drug leads.
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spelling pubmed-90568472022-05-04 Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery Abdelaleem, Enas Reda Samy, Mamdouh Nabil Desoukey, Samar Yehia Liu, Miaomiao Quinn, Ronald J. Abdelmohsen, Usama Ramadan RSC Adv Chemistry Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities. Sponges which belong to the order Dictyoceratida are distinctly classified into 5 families: Dysideidae, Irciniidae, Spongiidae, Thorectidae, and Verticilliitidae. In this review, compounds isolated from Dictyoceratida sponges were discussed with their biological potential within the period 2013 to December 2019. Moreover, analysis of the physicochemical properties of these marine natural products was investigated and the results showed that 78% of the compounds have oral bioavailability potential. This review highlights sponges of the order Dictyoceratida as exciting source for discovery of new drug leads. The Royal Society of Chemistry 2020-09-21 /pmc/articles/PMC9056847/ /pubmed/35514397 http://dx.doi.org/10.1039/d0ra04408c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Abdelaleem, Enas Reda
Samy, Mamdouh Nabil
Desoukey, Samar Yehia
Liu, Miaomiao
Quinn, Ronald J.
Abdelmohsen, Usama Ramadan
Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
title Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
title_full Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
title_fullStr Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
title_full_unstemmed Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
title_short Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery
title_sort marine natural products from sponges (porifera) of the order dictyoceratida (2013 to 2019); a promising source for drug discovery
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9056847/
https://www.ncbi.nlm.nih.gov/pubmed/35514397
http://dx.doi.org/10.1039/d0ra04408c
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