Cargando…

Eight-step total synthesis of (+)-crambescin A

(+)-Crambescin A belongs to the polycyclic guanidine natural product family and has been shown to possess various medically important properties. The chiral bicyclic guanidine structure of (+)-crambescin A presents a challenge for chemical synthesis. Here we implement a novel asymmetric Biginelli re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gao, Zhenhua, Li, Junchen, Song, Yunyang, Bi, Xiaojing, Meng, Xiangyan, Guo, Yongbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057376/ https://www.ncbi.nlm.nih.gov/pubmed/35518432 http://dx.doi.org/10.1039/d0ra08726b

Ejemplares similares

Regioselective O/C phosphorylation of α-chloroketones: a general method for the synthesis of enol phosphates and β-ketophosphonates via Perkow/Arbuzov reaction
por: Cao, Yuepeng, et al.
Publicado: (2020)

Copper-catalyzed stereo- and regioselective hydrophosphorylation of terminal alkynes: scope and mechanistic study
por: Li, Junchen, et al.
Publicado: (2022)

Organobase-catalyzed 1,1-diborylation of terminal alkynes under metal-free conditions
por: Li, Junchen, et al.
Publicado: (2022)

Efficient Synthesis of 3‐Mercaptoindoles via HI‐Promoted Sulfenylation of Indoles with Sodium Sulfinates
por: Sun, Shengnan, et al.
Publicado: (2023)

Chiral phosphoric acid-catalyzed enantioselective phosphinylation of 3,4-dihydroisoquinolines with diarylphosphine oxides
por: Guo, Yongbiao, et al.
Publicado: (2023)

Crambescin C1 Exerts a Cytoprotective Effect on HepG2 Cells through Metallothionein Induction
por: Roel, María, et al.
Publicado: (2015)

A bioinspired, one-step total synthesis of peshawaraquinone
por: Vieira de Castro, Tomás, et al.
Publicado: (2022)

Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect
por: Rubiolo, Juan A., et al.
Publicado: (2021)

Evaluation of General Synthesis Procedures for Bioflavonoid–Metal Complexes in Air-Saturated Alkaline Solutions
por: Yao, Yuanyong, et al.
Publicado: (2020)

Corrigendum: Evaluation of General Synthesis Procedures for Bioflavonoid–Metal Complexes in Air-Saturated Alkaline Solutions
por: Yao, Yuanyong, et al.
Publicado: (2020)

Total Chemical Synthesis of Modified Histones
por: Qi, Yun-Kun, et al.
Publicado: (2018)

Total Synthesis and Biological Evaluation of Kakeromamide A and Its Analogues
por: Zhao, Meng, et al.
Publicado: (2020)

A useful strategy for synthesis of the disaccharide of OSW-1
por: Wang, Bin, et al.
Publicado: (2023)

Total synthesis of crotophorbolone
por: Yu, Tianzi, et al.
Publicado: (2020)

Total synthesis of the putative structure of the proposed Banyasin A
por: Gao, Xuguang, et al.
Publicado: (2015)

Total synthesis of biselide A
por: Challa, Venugopal Rao, et al.
Publicado: (2021)

Asymmetric total synthesis of (+)-xestoquinone and (+)-adociaquinones A and B
por: Lu, Xiao-Long, et al.
Publicado: (2021)

Stereoselective synthesis of (E)-α,β-unsaturated esters: triethylamine-catalyzed allylic rearrangement of enol phosphates
por: Zhang, Yulong, et al.
Publicado: (2023)

Concise two-step chemical synthesis of molnupiravir
por: Pereira, Vinícius R. D., et al.
Publicado: (2022)

First total synthesis of concavine
por: Saint-Dizier, François, et al.
Publicado: (2017)

Advances in the Total Synthesis of Aflatoxins
por: Yang, Liyan, et al.
Publicado: (2021)

Total synthesis of bi-magnolignan
por: Lu, Si-Yuan, et al.
Publicado: (2023)

High acidity cellulose sulfuric acid from sulfur trioxide: a highly efficient catalyst for the one step synthesis of xanthene and dihydroquinazolinone derivatives
por: Yue, Xiaofei, et al.
Publicado: (2019)

Progress in the total synthesis of resin glycosides
por: Wang, Wenli, et al.
Publicado: (2022)

One-step, high-yield synthesis of g-C(3)N(4) nanosheets for enhanced visible light photocatalytic activity
por: Wang, Liyan, et al.
Publicado: (2019)

A convergent total synthesis of ouabagenin
por: Mukai, Ken, et al.
Publicado: (2015)

Total synthesis of (−)-scabrolide A and (−)-yonarolide
por: Hafeman, Nicholas J., et al.
Publicado: (2023)

An abiotic, tetrameric, eight-helix bundle
por: Menke, Friedericke S., et al.
Publicado: (2023)

The enantioselective total synthesis of laurendecumallene B
por: Taylor, Cooper A., et al.
Publicado: (2020)

Eight biomarkers on a novel strip for early diagnosis of acute myocardial infarction
por: Huang, Li, et al.
Publicado: (2019)

Ten-step asymmetric total syntheses of potent antibiotics anthracimycin and anthracimycin B
por: Tian, Peilin, et al.
Publicado: (2022)

Sequential cycloaddition and ring expansion reaction of arynes and methylenebenzothiopheneones: synthesis of a benzo-fused eight-membered ring via sulfonium ylides
por: Xiao, Peng, et al.
Publicado: (2019)

Studies on asymmetric total synthesis of (−)-β-hydrastine via a chiral epoxide ring-opening cascade cyclization strategy
por: Li, Jihui, et al.
Publicado: (2020)

Nineteen-Step Total Synthesis of (+)-Phorbol
por: Kawamura, Shuhei, et al.
Publicado: (2016)

11-Step Total Synthesis of Araiosamines
por: Tian, Maoqun, et al.
Publicado: (2016)

Catalytic graphitization assisted synthesis of Fe(3)C/Fe/graphitic carbon with advanced pseudocapacitance
por: Guo, Aoping, et al.
Publicado: (2022)

Efficient synthesis of epoxybutane from butanediol via a two-step process
por: Niu, Xin, et al.
Publicado: (2019)

Enantioselective total synthesis of (−)-myrifabral A and B
por: Fulton, Tyler J., et al.
Publicado: (2020)

A catalytic asymmetric total synthesis of (–)-perophoramidine
por: Trost, B. M., et al.
Publicado: (2015)

Total Synthesis and Antimicrobial Evaluation of Pagoamide A
por: Wu, Cheng-Han, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ieknqt7kolu8h0nn2ur6k1si7o