Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles

An efficient Rh(iii)-catalyzed synthesis of 2-arylindole derivatives via intermolecular C–H annulation of arylhydrazines with sulfoxonium ylides was accomplished. A variety of 2-acetyl-1-arylhydrazines with sulfoxonium ylides were converted into 2-arylindoles in satisfactory yields. Excellent select...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, He, Lu, Ye, Jin, Xinxin, Sun, Shuang, Duan, Limei, Liu, Jinghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057399/
https://www.ncbi.nlm.nih.gov/pubmed/35515363
http://dx.doi.org/10.1039/d0ra07701a
_version_ 1784697889080999936
author Li, He
Lu, Ye
Jin, Xinxin
Sun, Shuang
Duan, Limei
Liu, Jinghai
author_facet Li, He
Lu, Ye
Jin, Xinxin
Sun, Shuang
Duan, Limei
Liu, Jinghai
author_sort Li, He
collection PubMed
description An efficient Rh(iii)-catalyzed synthesis of 2-arylindole derivatives via intermolecular C–H annulation of arylhydrazines with sulfoxonium ylides was accomplished. A variety of 2-acetyl-1-arylhydrazines with sulfoxonium ylides were converted into 2-arylindoles in satisfactory yields. Excellent selectivity and good functional group tolerance of this transformation were also observed.
format Online
Article
Text
id pubmed-9057399
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90573992022-05-04 Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles Li, He Lu, Ye Jin, Xinxin Sun, Shuang Duan, Limei Liu, Jinghai RSC Adv Chemistry An efficient Rh(iii)-catalyzed synthesis of 2-arylindole derivatives via intermolecular C–H annulation of arylhydrazines with sulfoxonium ylides was accomplished. A variety of 2-acetyl-1-arylhydrazines with sulfoxonium ylides were converted into 2-arylindoles in satisfactory yields. Excellent selectivity and good functional group tolerance of this transformation were also observed. The Royal Society of Chemistry 2020-10-30 /pmc/articles/PMC9057399/ /pubmed/35515363 http://dx.doi.org/10.1039/d0ra07701a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, He
Lu, Ye
Jin, Xinxin
Sun, Shuang
Duan, Limei
Liu, Jinghai
Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
title Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
title_full Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
title_fullStr Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
title_full_unstemmed Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
title_short Rhodium(iii)-catalyzed C–H annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
title_sort rhodium(iii)-catalyzed c–h annulation of 2-acetyl-1-arylhydrazines with sulfoxonium ylides: synthesis of 2-arylindoles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057399/
https://www.ncbi.nlm.nih.gov/pubmed/35515363
http://dx.doi.org/10.1039/d0ra07701a
work_keys_str_mv AT lihe rhodiumiiicatalyzedchannulationof2acetyl1arylhydrazineswithsulfoxoniumylidessynthesisof2arylindoles
AT luye rhodiumiiicatalyzedchannulationof2acetyl1arylhydrazineswithsulfoxoniumylidessynthesisof2arylindoles
AT jinxinxin rhodiumiiicatalyzedchannulationof2acetyl1arylhydrazineswithsulfoxoniumylidessynthesisof2arylindoles
AT sunshuang rhodiumiiicatalyzedchannulationof2acetyl1arylhydrazineswithsulfoxoniumylidessynthesisof2arylindoles
AT duanlimei rhodiumiiicatalyzedchannulationof2acetyl1arylhydrazineswithsulfoxoniumylidessynthesisof2arylindoles
AT liujinghai rhodiumiiicatalyzedchannulationof2acetyl1arylhydrazineswithsulfoxoniumylidessynthesisof2arylindoles

Ejemplares similares