Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus

The trace element iron affects immune responses and vaccination, but knowledge of its role in autoimmune diseases is limited. Expansion of pathogenic T cells, especially T follicular helper (Tfh) cells, has great significance to systemic lupus erythematosus (SLE) pathogenesis. Here, we show an impor...

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Detalles Bibliográficos
Autores principales: Gao, Xiaofei, Song, Yang, Wu, Jiali, Lu, Shuang, Min, Xiaoli, Liu, Limin, Hu, Longyuan, Zheng, Meiling, Du, Pei, Yu, Yaqin, Long, Hai, Wu, Haijing, Jia, Sujie, Yu, Di, Lu, Qianjin, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057600/
https://www.ncbi.nlm.nih.gov/pubmed/35499082
http://dx.doi.org/10.1172/JCI152345

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