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Targeting fatty acid β-oxidation impairs monocyte differentiation and prolongs heart allograft survival

Monocytes play an important role in the regulation of alloimmune responses after heart transplantation (HTx). Recent studies have highlighted the importance of immunometabolism in the differentiation and function of myeloid cells. While the importance of glucose metabolism in monocyte differentiatio...

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Detalles Bibliográficos
Autores principales: Zhu, Yuehui, Dun, Hao, Ye, Li, Terada, Yuriko, Shriver, Leah P., Patti, Gary J., Kreisel, Daniel, Gelman, Andrew E., Wong, Brian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057610/
https://www.ncbi.nlm.nih.gov/pubmed/35239515
http://dx.doi.org/10.1172/jci.insight.151596