Microbiota dynamics in a randomized trial of gut decontamination during allogeneic hematopoietic cell transplantation

BACKGROUND: Gut decontamination (GD) can decrease the incidence and severity of acute graft-versus-host disease (aGVHD) in murine models of allogeneic hematopoietic cell transplantation (HCT). In this pilot study, we examined the impact of GD on gut microbiome composition and the incidence of aGVHD...

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Detalles Bibliográficos
Autores principales: Severyn, Christopher J., Siranosian, Benjamin A., Kong, Sandra Tian-Jiao, Moreno, Angel, Li, Michelle M., Chen, Nan, Duncan, Christine N., Margossian, Steven P., Lehmann, Leslie E., Sun, Shan, Andermann, Tessa M., Birbrayer, Olga, Silverstein, Sophie, Reynolds, Carol G., Kim, Soomin, Banaei, Niaz, Ritz, Jerome, Fodor, Anthony A., London, Wendy B., Bhatt, Ami S., Whangbo, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057614/
https://www.ncbi.nlm.nih.gov/pubmed/35239511
http://dx.doi.org/10.1172/jci.insight.154344

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