Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms

As blood transitions from steady laminar flow (S-flow) in healthy arteries to disturbed flow (D-flow) in aneurysmal arteries, platelets are subjected to external forces. Biomechanical platelet activation is incompletely understood and is a potential mechanism behind antiplatelet medication resistanc...

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Detalles Bibliográficos
Autores principales: Morrell, Craig N., Mix, Doran, Aggarwal, Anu, Bhandari, Rohan, Godwin, Matthew, Owens, Phillip, Lyden, Sean P., Doyle, Adam, Krauel, Krystin, Rondina, Matthew T., Mohan, Amy, Lowenstein, Charles J., Shim, Sharon, Stauffer, Shaun, Josyula, Vara Prasad, Ture, Sara K., Yule, David I., Wagner, Larry E., Ashton, John M., Elbadawi, Ayman, Cameron, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057618/
https://www.ncbi.nlm.nih.gov/pubmed/35324479
http://dx.doi.org/10.1172/JCI152373

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