NOGOB receptor deficiency increases cerebrovascular permeability and hemorrhage via impairing histone acetylation–mediated CCM1/2 expression

The loss function of cerebral cavernous malformation (CCM) genes leads to most CCM lesions characterized by enlarged leaking vascular lesions in the brain. Although we previously showed that NOGOB receptor (NGBR) knockout in endothelial cells (ECs) results in cerebrovascular lesions in the mouse emb...

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Detalles Bibliográficos
Autores principales: Fang, Zhi, Sun, Xiaoran, Wang, Xiang, Ma, Ji, Palaia, Thomas, Rana, Ujala, Miao, Benjamin, Ragolia, Louis, Hu, Wenquan, Miao, Qing Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057619/
https://www.ncbi.nlm.nih.gov/pubmed/35316220
http://dx.doi.org/10.1172/JCI151382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057619/
https://www.ncbi.nlm.nih.gov/pubmed/35316220
http://dx.doi.org/10.1172/JCI151382

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