Gut-derived bacterial toxins impair memory CD4(+) T cell mitochondrial function in HIV-1 infection

People living with HIV (PLWH) who are immune nonresponders (INRs) are at greater risk of comorbidity and mortality than are immune responders (IRs) who restore their CD4(+) T cell count after antiretroviral therapy (ART). INRs have low CD4(+) T cell counts (<350 c/μL), heightened systemic inflamm...

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Detalles Bibliográficos
Autores principales: Ferrari, Brian, Da Silva, Amanda Cabral, Liu, Ken H., Saidakova, Evgeniya V., Korolevskaya, Larisa B., Shmagel, Konstantin V., Shive, Carey, Pacheco Sanchez, Gabriela, Retuerto, Mauricio, Sharma, Ashish Arunkumar, Ghneim, Khader, Noel-Romas, Laura, Rodriguez, Benigno, Ghannoum, Mahmoud A., Hunt, Peter P., Deeks, Steven G., Burgener, Adam D., Jones, Dean P., Dobre, Mirela A., Marconi, Vincent C., Sekaly, Rafick-Pierre, Younes, Souheil-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057623/
https://www.ncbi.nlm.nih.gov/pubmed/35316209
http://dx.doi.org/10.1172/JCI149571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057623/
https://www.ncbi.nlm.nih.gov/pubmed/35316209
http://dx.doi.org/10.1172/JCI149571

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