Mutant ANP induces mitochondrial and ion channel remodeling in a human iPSC–derived atrial fibrillation model

Human induced pluripotent stem cell–derived cardiomyocytes (iPSC-CMs) can model heritable arrhythmias to personalize therapies for individual patients. Although atrial fibrillation (AF) is a leading cause of cardiovascular morbidity and mortality, current platforms to generate iPSC-atrial (a) CMs ar...

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Detalles Bibliográficos
Autores principales: Ly, Olivia T., Chen, Hanna, Brown, Grace E., Hong, Liang, Wang, Xinge, Han, Yong Duk, Pavel, Mahmud Arif, Sridhar, Arvind, Maienschein-Cline, Mark, Chalazan, Brandon, Ong, Sang-Ging, Abdelhady, Khaled, Massad, Malek, Rizkallah, Lona Ernst, Rehman, Jalees, Khetani, Salman R., Darbar, Dawood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057627/
https://www.ncbi.nlm.nih.gov/pubmed/35393944
http://dx.doi.org/10.1172/jci.insight.155640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057627/
https://www.ncbi.nlm.nih.gov/pubmed/35393944
http://dx.doi.org/10.1172/jci.insight.155640

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