Cargando…

Clinical and Genomic Profiles of Korean Patients with MECOM Rearrangement and the t(3;21)(q26.2;q22.1) Translocation

The translocation (3;21)(q26.2;q22.1) is a unique cytogenetic aberration that characterizes acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) in patients with AML and myelodysplastic syndrome (MDS) or a therapy-related myeloid neoplasm. Using multigene target sequencing and FISH,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jikyo, Kim, Sung Min, Kim, Soonok, Yun, Jiwon, Jeong, Dajeong, Lee, Young Eun, Roh, Eun-Youn, Lee, Dong Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Laboratory Medicine 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057822/ https://www.ncbi.nlm.nih.gov/pubmed/35470277 http://dx.doi.org/10.3343/alm.2022.42.5.590

Ejemplares similares

3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features
por: Tang, Zhenya, et al.
Publicado: (2023)

An Interstitial Deletion at 10q26.2q26.3
por: Iourov, Ivan Y., et al.
Publicado: (2014)

Characteristics and clinical outcomes of patients with acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2)
por: Richard-Carpentier, Guillaume, et al.
Publicado: (2023)

Emergence of t(3;21)(q26.2;q22) during eltrombopag treatment in a patient with relapsed aplastic anemia who received chemotherapy for angioimmunoblastic T-cell lymphoma
por: Nakamura, Fumi, et al.
Publicado: (2022)

Targeting ncRNAs in the 3q26.2 amplicon
por: Chaluvally-Raghavan, Pradeep, et al.
Publicado: (2015)

A Case of Inherited t(4;10)(q26;q26.2) Chromosomal Translocation Elucidated by Multiple Chromosomal and Molecular Analyses. Case Report and Review of the Literature
por: Popescu, Roxana, et al.
Publicado: (2021)

De novo balanced reciprocal translocation t(2;3)(q31;q27) in a fetus conceived using PGD in a t(2;14)(q35;q32.1) balanced reciprocal translocation carrier mother
por: Kim, Ji Won, et al.
Publicado: (2017)

伴t(3;21)(q26;q22)髓系肿瘤临床分析
Publicado: (2019)

De novo unbalanced translocation t(15;22)(q26.2;q12) with velo-cardio-facial syndrome: A case report and review of the literature
por: Gug, Cristina, et al.
Publicado: (2018)

Mapping Breakpoints of Complex Chromosome Rearrangements Involving a Partial Trisomy 15q23.1-q26.2 Revealed by Next Generation Sequencing and Conventional Techniques
por: Pan, Qiong, et al.
Publicado: (2016)

Characterization of an unbalanced translocation causing 3q28qter duplication and 10q26.2qter deletion in a patient with global developmental delay and self-injury
por: Osei-Owusu, Ikeoluwa A., et al.
Publicado: (2020)

A primary pediatric acute myelomonocytic leukemia with t(3;21)(q26;q22): A case report
por: Duan, Jia-xin, et al.
Publicado: (2023)

Pediatric chronic myeloid leukemia with inv(3)(q21q26.2) and T lymphoblastic transformation: a case report
por: Lewen, Margaret, et al.
Publicado: (2016)

Mild Phenotype in a Patient with a De Novo 6.3 Mb Distal Deletion at 10q26.2q26.3
por: Tanteles, George A., et al.
Publicado: (2015)

Data on MECOM rearrangement-driven chromosomal aberrations in myeloid malignancies
por: Tang, Zhenya, et al.
Publicado: (2019)

Acute myeloid leukemia with t(3;21)(q26.2;q22) developing following low-dose methotrexate therapy for rheumatoid arthritis and expressing two AML1/MDS1/EVI1 fusion proteins: A case report
por: Tanaka, Keisuke, et al.
Publicado: (2017)

LSAMP Rearrangement in Acute Myeloid Leukemia With a Jumping Translocation Involving 3q13.31
por: Yoon, Jung, et al.
Publicado: (2021)

Identification of novel candidate target genes, including EPHB3, MASP1 and SST at 3q26.2–q29 in squamous cell carcinoma of the lung
por: Kang, Ji Un, et al.
Publicado: (2009)

Absence epilepsy and the CHD2 gene: an adolescent male with moderate intellectual disability, short-lasting psychoses, and an interstitial deletion in 15q26.1–q26.2
por: Verhoeven, Willem MA, et al.
Publicado: (2016)

Pure 16q21q22.1 deletion in a complex rearrangement possibly caused by a chromothripsis event
por: Genesio, Rita, et al.
Publicado: (2013)

Detection of RUNX1-MECOM Fusion Gene and t(3;21) in a Very Elderly Patient Having Acute Myeloid Leukemia with Myelodysplasia-Related Changes
por: Yang, John Jeongseok, et al.
Publicado: (2012)

Infantile spasms with periventricular nodular heterotopia, unbalanced chromosomal translocation 3p26.2 ‐10p15.1 and 6q22.31 duplication
por: Jones, Kevin, et al.
Publicado: (2016)

Amplification of 3q26.2, 5q14.3, 8q24.3, 8q22.3, and 14q32.33 Are Possible Common Genetic Alterations in Oral Cancer Patients
por: Ambele, Melvin A., et al.
Publicado: (2020)

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1
por: Cai, Qiuyin, et al.
Publicado: (2014)

A new mosaic der(18)t(1;18)(q32.1;q21.3) with developmental delay and facial dysmorphism
por: Choi, Young-Jin, et al.
Publicado: (2016)

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
por: Houlston, Richard S, et al.
Publicado: (2010)

Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression
por: Gu, Jun, et al.
Publicado: (2015)

Clinical, Cytogenetic, and Biochemical Analyses of a Family with a t(3;13)(q26.2;p11.2): Further Delineation of 3q Duplication Syndrome
por: Abreu-González, M., et al.
Publicado: (2013)

Cytogenomic characterization of 1q43q44 deletion associated with 4q32.1q35.2 duplication and phenotype correlation
por: Mohamed, A. M., et al.
Publicado: (2018)

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk
por: Chubb, Daniel, et al.
Publicado: (2013)

A case of de novo duplication of 15q24-q26.3
por: Kim, Eun Young, et al.
Publicado: (2011)

Shank3 Mice Carrying the Human Q321R Mutation Display Enhanced Self-Grooming, Abnormal Electroencephalogram Patterns, and Suppressed Neuronal Excitability and Seizure Susceptibility
por: Yoo, Ye-Eun, et al.
Publicado: (2019)

Paternally derived translocation t(8;18)(q22.1;q22)pat associated in a patient with developmental delay: Case report and review
por: Rao, Lakshmi, et al.
Publicado: (2010)

Mutations and karyotype in myelodysplastic syndromes: TP53 clusters with monosomal karyotype, RUNX1 with trisomy 21, and SF3B1 with inv(3)(q21q26.2) and del(11q)
por: Tefferi, Ayalew, et al.
Publicado: (2017)

Molecular characterization of the rare translocation t(3;10)(q26;q21) in an acute myeloid leukemia patient
por: Jancuskova, Tereza, et al.
Publicado: (2014)

Various endocrine disorders in children with t(13;14)(q10;q10) Robertsonian translocation
por: Choi, Byung Ho, et al.
Publicado: (2013)

A novel chromosome 2q24.3‐q32.1 microdeletion in a fetus with multiple malformations
por: Zhu, Mianmian, et al.
Publicado: (2022)

Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations
por: Quistrebert, Jocelyn, et al.
Publicado: (2021)

Biallelic BCL6 rearrangements by dual t(3;14)(q27;q32) and t(3;22)(q27;q11) translocations in diffuse large B-cell lymphoma
por: Nakamura, Yuichi, et al.
Publicado: (2022)

Complex 4q35 and 10q26 Rearrangements: A Challenge for Molecular Diagnosis of Patients With Facioscapulohumeral Dystrophy
por: Delourme, Megane, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_r2oeglqcq373h1l6bcd13scv3n