Synthesis of dihydroisoindolo[2,1-a]quinolin-11-ones, their in silico ADMET properties and in vitro antitumor activities

We evaluated the antitumoral activity of diverse series of 5-aryl-dihydroisoindolo[2,1-a]quinolin-11-ones, AIIQ (Aryl IsoIndolo-Quinoline, 4a–m), and 5-vinyl dihydroisoindolo[2,1-a]quinolin-11-ones, VIIQ (Vinyl IsoIndolo-Quinoline, 6a–l), obtained using three component imino Diels–Alder (DA) reactio...

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Detalles Bibliográficos
Autores principales: Merchán-Arenas, Diego R., Sojo, Felipe, Arvelo, Francisco, Kouznetsov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057833/
https://www.ncbi.nlm.nih.gov/pubmed/35516784
http://dx.doi.org/10.1039/d0ra04555a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057833/
https://www.ncbi.nlm.nih.gov/pubmed/35516784
http://dx.doi.org/10.1039/d0ra04555a

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