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Development of a High-Throughput Screening Assay for Small-Molecule Inhibitors of Androgen Receptor Splice Variants

The role of the androgen receptor (AR) in the progression of prostate cancer (PCa) is well established and competitive inhibition of AR ligand binding domain (LBD) has been the mainstay of antiandrogen therapies for advanced and metastatic disease. However, the efficacy of such drugs is often limite...

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Detalles Bibliográficos
Autores principales:	Monaghan, Amy E., Porter, Alison, Hunter, Irene., Morrison, Angus, McElroy, Stuart P., McEwan, Iain J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057896/ https://www.ncbi.nlm.nih.gov/pubmed/35333596 http://dx.doi.org/10.1089/adt.2021.128

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