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Improving the Yield and Quality of Daptomycin in Streptomyces roseosporus by Multilevel Metabolic Engineering

Daptomycin is a cyclic lipopeptide antibiotic with a significant antibacterial action against antibiotic-resistant Gram-positive bacteria. Despite numerous attempts to enhance daptomycin yield throughout the years, the production remains unsatisfactory. This study reports the application of multilev...

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Detalles Bibliográficos
Autores principales:	Lyu, Zhong-Yuan, Bu, Qing-Ting, Fang, Jiao-Le, Zhu, Chen-Yang, Xu, Wei-Feng, Ma, Lie, Gao, Wen-Li, Chen, Xin-Ai, Li, Yong-Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058172/ https://www.ncbi.nlm.nih.gov/pubmed/35509317 http://dx.doi.org/10.3389/fmicb.2022.872397

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