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QSPR model for Caco-2 cell permeability prediction using a combination of HQPSO and dual-RBF neural network
The Caco-2 cell model is widely used to evaluate the in vitro human intestinal permeability of drugs due to its morphological and functional similarity to human enterocytes. Although it is safe and relatively economic, it is time-consuming. A rapid and accurate quantitative structure-property relati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society of Chemistry
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058322/ https://www.ncbi.nlm.nih.gov/pubmed/35514900 http://dx.doi.org/10.1039/d0ra08209k |