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Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting miR-766-3p/ADAMTS5 axis

The aim of this study was to explore the role of hsa_circRNA_0000205 (circ_0000205) in chondrocyte injury in osteoarthritis (OA) and the underlying mechanism. Expression of circ_0000205, microRNA (miR)-766-3p and a disintegrin and metalloproteinase with thrombospondin motif (ADAMTS)-5 was detected b...

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Detalles Bibliográficos
Autores principales:	Li, Guowen, Luo, Heyuan, Ding, Zhiyong, Liang, Haofeng, Lai, Zhoupeng, Chen, Shuzhen, Huang, Yuliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058376/ https://www.ncbi.nlm.nih.gov/pubmed/35484121 http://dx.doi.org/10.1177/17534259221077078

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