Linear consecutive hexaoxazoles as G4 ligands inducing chair-type anti-parallel topology of a telomeric G-quadruplex

G-quadruplex structures (G4s) in guanine-rich regions of DNA play critical roles in various biological phenomena, including replication, translation, and gene expression. There are three types of G4 topology, i.e., parallel, anti-parallel, and hybrid, and ligands that selectively interact with or st...

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Detalles Bibliográficos
Autores principales: Sasaki, Shogo, Ma, Yue, Ishizuka, Takumi, Bao, Hong-Liang, Hirokawa, Takatsugu, Xu, Yan, Tera, Masayuki, Nagasawa, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058415/
https://www.ncbi.nlm.nih.gov/pubmed/35519695
http://dx.doi.org/10.1039/d0ra09413g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058415/
https://www.ncbi.nlm.nih.gov/pubmed/35519695
http://dx.doi.org/10.1039/d0ra09413g

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