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Linear consecutive hexaoxazoles as G4 ligands inducing chair-type anti-parallel topology of a telomeric G-quadruplex
G-quadruplex structures (G4s) in guanine-rich regions of DNA play critical roles in various biological phenomena, including replication, translation, and gene expression. There are three types of G4 topology, i.e., parallel, anti-parallel, and hybrid, and ligands that selectively interact with or st...
Autores principales: | Sasaki, Shogo, Ma, Yue, Ishizuka, Takumi, Bao, Hong-Liang, Hirokawa, Takatsugu, Xu, Yan, Tera, Masayuki, Nagasawa, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058415/ https://www.ncbi.nlm.nih.gov/pubmed/35519695 http://dx.doi.org/10.1039/d0ra09413g |
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